> Absolute granulocytopenias with relative lymphocytosis (p. > Constitutional relative lymphocytosis, which can reach up to 60% and occurs without apparent reason (mostly in asthenic teenagers). > Hyperthyroidism and Addison disease, which show relative lymphocy-tosis. > Chickenpox, measles, and brucellosis, in which a less well-developed relative lymphocytosis is found, and the counts remain within the normal range. Lymphocyte counts may increase to > 50 000/^l. > Infectious lymphocytosis, a pediatric infectious disease with fever of short duration. > Whooping cough (pertussis) with clear leukocytosis and total lymphocyte counts up to 20 000 and even 50 000/^l occasionally, slightly plasmacytoid differentiation. Morphologically normal lymphocytes predominate in the blood analyses in the following diseases:
Although the granulocyte count is relatively reduced, its absolute value (per microliter) rarely falls below the lower limit of normal values. Unlike the case in acute leukemias, erythrocyte and thrombocyte counts are not significantly reduced. This is usually seen as enlarged nuclei, a moderately loose, coarse chromatin structure, and a marked widening of the basophilic cytoplasmic layer.Ĭlinical findings, which include acute fever symptoms, enlarged lymph nodes, and sometimes exanthema, help to identify a lymphatic reactive state. Lymphatic cells show wide variability and transform easily.